Medicine is one of the most important tools that doctors use to treat and control diseases. If you want the medicine to work fully and see the expected treatment results, taking the medicine in the correct dosage and time as recommended by your doctor or pharmacist is very important.
But did you know that taking medicine alone may not be enough? Because sometimes some medicines can react with certain foods, which may affect the effectiveness of the medicine or cause unwanted side effects. And 2 types of fruits that affect taking medicine are “pomelo” and “grapefruit”.
Why is it forbidden to take medicine with “pomelo” and “grapefruit”?
Experts have found that pomelo and grapefruit contain a substance called “furanocoumarin”, especially “bergamottin”, which inhibits the function of an enzyme in our body. This enzyme plays an important role in removing drugs from the body. When it is inhibited, the drug is removed more slowly, resulting in a higher amount of drug in the body than normal, and it can cause severe side effects.
Grapefruit is a tropical fruit that we are familiar with. It originated from the Caribbean Islands. Scientists have found that grapefruit is a crossbreeding between a เล่นบาคาร่า UFABET เว็บตรง ค่าคอมสูง type of orange in the Cheng or sweet orange group and a Malaysian pomelo, making grapefruit and pomelo classified in the citrus family.
These medicines cannot be taken with grapefruit or pomelo.
- Blood lipid-lowering drugs: such as simvastatin, atorvastatin, lovastatin
- Antihypertensive drugs: such as nifedipine, filodipine, losartan
- Immunosuppressive drugs: such as cyclosporine
- Steroids: such as budesonide
- Mood-boosting medications: such as buspirone, sertraline
- Heart medications: such as amiodarone, dronedarone
- Antihistamines: such as fexofenadine
- Antiviral drugs: such as saquinavir
- Antibiotics: such as erythromycin
- Anthelmintics: such as albendazole
- Drugs for treating erectile dysfunction: such as sildenafil
- Medicines for the treatment of enlarged prostate: such as silodosin
- Anticoagulants: such as epixaban, rivaroxaban
If you are taking any medications, always consult your pharmacist before taking grapefruit or pomelo, to be on the safe side.
Grapefruit and pomelo can still affect the drug for up to 3 days.
Many people may misunderstand that eating pomelo or grapefruit will affect the medicine only when taken together. But in fact, the effects of substances in pomelo and grapefruit on the body can last up to 3 days.